Research Areas
Research Areas
- Bioinformatic discovery of novel pharmaceutical targets, specifically in the area of vascular diseases and angiogenesis.
- Computational modeling and systems biology of angiogenesis.
- Computational modeling and systems biology of the heart, with applications to clinical problems
- Computational modeling of how regulatory elements in DNA sequences are structured to control gene expression.
- Development of new machine learning methods for analysis of high throughput data.
- Large scale annotation of human genetic variation.
- Network modeling of protein-protein interactions.
- Predicting the impact of somatic variation in cancer genomes with molecular modeling and comparative genomics.
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