- Q. What is Bioinformatic ?
Ans. The mathematical, statistical and computing methods that aim to solve biological problems using
DNA and amino acid sequences and related information is known as Bioinformatic.
- Q.Why do you think Bioinformatic is important?
Ans. Today, we can use computers to access much more biological data than ever before. You can learn
a lot by analysing this data.
For example, you can identify genes by comparing genomic data across organisms and identifying patterns in the data.
Insights as to the structure of proteins can be obtained through computer analyses of the protein sequences.
These approaches are a lot faster and a lot cheaper than relying solely on wet lab or Xray crystallographic techniques.
Of course, computational techniques are often not as reliable as getting the firsthand
view of the molecules.
Clearly, you need both worlds: you need to take advantage of the computer tools when you know
the predictions are reliable and use the more expensive techniques (in the wet lab) when you can’t
get away from it
- Q. What do you think, are the more intresting areas of Bioinformatic
Ans. Looking at what the academic world is publishing, microarray research is really hot right now, and
people haven't quite figured out what the best way is (some might argue if we should even be trying)
to store, process, and understand this data, but there are lots of interesting ideas.
- Q. How can you have Accession number?
Ans. Accession number (bioinformatic), a unique identifier given to a biological polymer sequence (DNA,
protein) when it is submitted to a sequence database.
- Q. In the next 2 or 3 years what will the important advances in the field will be?
Ans. The sequencing of the human genome has just been completed and in the next two or three years I
expect progress will be made in identifying the genes. Right now, we don’t even know how many
genes we have! Also, in the next two or three years, we’ll be learning more about the structure and
function of proteins in the cell. Hopefully, in the longer term we’ll be able to piece together that information to get a more complete picture of regulatory networks in the cell.
Ans. The mathematical, statistical and computing methods that aim to solve biological problems using DNA and amino acid sequences and related information is known as Bioinformatic.
Ans. Today, we can use computers to access much more biological data than ever before. You can learn a lot by analysing this data.
For example, you can identify genes by comparing genomic data across organisms and identifying patterns in the data.
Insights as to the structure of proteins can be obtained through computer analyses of the protein sequences.
These approaches are a lot faster and a lot cheaper than relying solely on wet lab or Xray crystallographic techniques.
Of course, computational techniques are often not as reliable as getting the firsthand view of the molecules.
Clearly, you need both worlds: you need to take advantage of the computer tools when you know the predictions are reliable and use the more expensive techniques (in the wet lab) when you can’t get away from it
Ans. Looking at what the academic world is publishing, microarray research is really hot right now, and people haven't quite figured out what the best way is (some might argue if we should even be trying) to store, process, and understand this data, but there are lots of interesting ideas.
Ans. Accession number (bioinformatic), a unique identifier given to a biological polymer sequence (DNA, protein) when it is submitted to a sequence database.
Ans. The sequencing of the human genome has just been completed and in the next two or three years I expect progress will be made in identifying the genes. Right now, we don’t even know how many genes we have! Also, in the next two or three years, we’ll be learning more about the structure and function of proteins in the cell. Hopefully, in the longer term we’ll be able to piece together that information to get a more complete picture of regulatory networks in the cell.
