Friday, April 17, 2020

Basic Bioinformatics Terms on letter B

Basic Bioinformatics Terms on letter A
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These are Basic Bioinformatics Terms on letter B. These Basic Bioinformatics Terms on letter B. It can boost vocabulary in bioinformatics. It can also enhance basic knowledge of Bioinformatics.
1. What is "Bacterial artificial chromosome(BAC)"?

    Bacterial artificial chromosome (BAC)- It is a cloning vector replicated in bacteria that can hold an insert of about 150,000 base pairs.



2. What is "BAM file "?

    BAM file - It is a binary version of a SAM file, the format is .bam.


3. What is a "BankIt"?

    BankIt - It is a computer program developed by the NCBI for submitting your own sequences to GenBank.


4. What is a "Binomial"?

    Binomial - It is a probability model for counting the number of ‘successes’ in an experiment with two possible outcomes.


5. Define "Bioinformatics".

    Bioinformatics - It is a field of study that extracts biological information from large data sets such as sequences, protein interactions, microarrays, etc. This field also includes the area of data visualization.


6. Define "Biological process".

    Biological process - It is a term coined by Gene Ontology to describe broad cellular outcomes, such as mitosis or energy production, that are accomplished by ordered assemblies of molecules.







7. What is a "Blast" in Bioinformatics?

    BLAST - It is the protein and nucleic acid sequence search engine developed at NCBI that allows you to search sequence databases. BLASTn searches for nucleotide sequences, BLASTp searches for amino acid sequences; BLAST2 compares 2 sequences.


8. What is "BLOSOM"?

    BLOSUM, block scoring matrix, a popular substitution matrix for aligning protein sequences.


9. What is "Bootstrap analysis"?

    Bootstrap analysis - it is a statistical technique used to assess the reliability of the branching structure in phylogenetic trees.


10. What is "Bowtie"?

    Bowtie - It is a software that maps short DNA sequences to a reference genome.




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