Bioinformatics MCQs Part 13

1. A _______ is defined in SCOP as a collection of superfamilies.

• primary structure of protein
• secondary structure of protein
• protein fold
• mutated protein sequences

2. DDD stands for ________.

• Dali Domain Dictionary.
• Distance Matrix Alignment Server.
• Distance Matrix Domain Dictionar.
• Distance Domain Dictionary.

3. Which one of the following helps to calculate a structural similarity measure between pairs of structures of protein chains taken from the PDB?

• CATH
• SCOP
• FSSP
• DALI

4. Template based protein modeling techniques is called as ________.

• comparative modeling.
• surface modeling.
• threading.
• abinitio prediction.

5. Which is the only method that permits for the incorporation of alignable gaps as characters?

• Maximum parsimony.
• Maximum likelihood.
• Neighbor Joining.
• Unweighted pair group method with arithmetic mean.

6. Which of these methods is a distance-based method in tree construction?

• Unweighted pair group method with arithmetic mean.
• Jukes-Cantor.
• Minimum evolution.
• Maximum parsimony.

7. Which one of the following is not a character-based method in tree construction?

• Maximum parsimony.
• Minimum likelihood.
• Minimum evolution method.
• Neighbor joining.

8. PAUP stands for ________.

• Phylogenetic Analysis Using Parsimony.
• Phylogenetic Analysis Using Pairwise.
• Proteomic Analysis Using Parsimony.
• Phylogenetic Analysis Using Protein.

9. A tree representation of a family showing the relationships between members and pattern of inheritance of a given trait is known as _______.

• pedigree.
• physical Map.
• genetic map.
• population studies.

10. The study of evolutionary relationship is ________.

• Phylogenics
• Molecular Evolution
• Cladogenesis
• Cladistics

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